Article
Family and genetic studies of indices of insulin sensitivity and insulin secretion in Pima Indians.
Diabetes/metabolism research and reviews - 1 Jan 2000
Hanson R L, Imperatore G, Narayan K M, Roumain J, Fagot-Campagna A, Pettitt D J, Bennett P H, Knowler W C
Abstract excerpt
BACKGROUND: The present analyses were conducted to examine the extent to which insulin sensitivity and insulin secretion, assessed using simple indices derived from an oral glucose tolerance test, are influenced by genetic factors, and to assess whether these genetic factors overlap with those influencing susceptibility to type 2 diabetes in Pima Indians. METHODS: Indices calculated from fasting and 2-h post-load...
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