Article
Cognitive and neural correlates of the 5-repeat allele of the dopamine D4 receptor gene in a population lacking the 7-repeat allele.
NeuroImage - 15 Apr 2015
Takeuchi Hikaru, Tomita Hiroaki, Taki Yasuyuki, Kikuchi Yoshie, Ono Chiaki, Yu Zhiqian, Sekiguchi Atsushi, Nouchi Rui, Kotozaki Yuka, Nakagawa Seishu, Miyauchi Carlos Makoto, Iizuka Kunio, Yokoyama Ryoichi, Shinada Takamitsu, Yamamoto Yuki, Hanawa Sugiko, Araki Tsuyoshi, Hashizume Hiroshi, Kunitoki Keiko, Sassa Yuko, Kawashima Ryuta
Abstract excerpt
The 5-repeat allele of a common length polymorphism in the gene that encodes the dopamine D4 receptor (DRD4) is robustly associated with the risk of attention deficit hyperactivity disorder (ADHD) and substantially exists in Asian populations, which have a lower ADHD prevalence. In this study, we investigated the effect of this allele on microstructural properties of the brain and on its functional activity...
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