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Article

Genetic factors of reaction time performance: DRD4 7-repeat allele associated with slower responses.

Genes, brain, and behavior - 1 Mar 2011

Szekely A, Balota D A, Duchek J M, Nemoda Z, Vereczkei A, Sasvari-Szekely M

Abstract excerpt

Twin studies indicate substantial inherited components in cognitive abilities. One of the most extensively studied candidate genes of cognitive functioning is the dopamine D4 receptor gene (DRD4), which has been suggested to be related to attentional disorders. Based on reaction time data of 245...

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Source

Identifiers

PMID: 20807239
DOI: 10.1111/j.1601-183X.2010.00645.x

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20807239-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Genetic factors of reaction time performance: DRD4 7-repeat allele associated with slower responses.PMID 20807239Read ↗

The short DRD4 repeats confer risk to attention deficit hyperactivity disorder in a family-based design and impair performance on a continuous performance test (TOVA).Semantic proximity Read ↗

Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention.Semantic proximity Read ↗

The dopamine receptor D4 7-repeat allele influences neurocognitive functioning, but this effect is moderated by age and ADHD status: an exploratory study.Semantic proximity Read ↗

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Absence of the 7-repeat variant of the DRD4 VNTR is associated with drifting sustained attention in children with ADHD but not in controls.Semantic proximity Read ↗

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