Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The short DRD4 repeats confer risk to attention deficit hyperactivity disorder in a family-based design and impair performance on a continuous performance test (TOVA).

Molecular psychiatry - 1 Jan 2002

Manor I, Tyano S, Eisenberg J, Bachner-Melman R, Kotler M, Ebstein R P

Abstract excerpt

One particular candidate gene, the dopamine D4 receptor (DRD4), has been the focus of intense study regarding ADHD since the original investigation by La Hoste et al, an observation confirmed by a recent metaanalysis. However, two previous studies from Israel failed to observe this association. We have now recruited an additional sample and, overall, in the combined sample of 178 triads we observe using the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Attention Deficit Disorder with Hyperactivity
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Family Health

Share to Linkage Disequilibrium

Share to Neuropsychological Tests

Share to Receptors, Dopamine D2

Share to Receptors, Dopamine D4

Share to Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 12192625
DOI: 10.1038/sj.mp.4001078

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The short DRD4 repeats confer risk to attention deficit hyperactivity disorder in a family-based design and impair performance on a continuous performance test (TOVA).PMID 12192625Read ↗

Association between DRD4 gene and performance of children with ADHD in a test of sustained attention.Semantic proximity Read ↗

Association of the dopamine D5 receptor with attention deficit hyperactivity disorder (ADHD) and scores on a continuous performance test (TOVA).Semantic proximity Read ↗

DRD4 gene variants and sustained attention in attention deficit hyperactivity disorder (ADHD): effects of associated alleles at the VNTR and -521 SNP.Semantic proximity Read ↗

Attention deficit/hyperactivity disorder children with a 7-repeat allele of the dopamine receptor D4 gene have extreme behavior but normal performance on critical neuropsychological tests of attention.Semantic proximity Read ↗

ADHD: relation between cognitive characteristics and DAT1 / DRD4 dopamine polymorphismsSemantic proximity Read ↗

An exploratory study of the relationship between four candidate genes and neurocognitive performance in adult ADHDSemantic proximity Read ↗

Association of the dopamine D4 receptor gene 7-repeat allele with neuropsychological test performance of children with ADHD.Semantic proximity Read ↗

DRD4 genotyping may differentiate symptoms of attention-deficit/hyperactivity disorder and sluggish cognitive tempo.Semantic proximity Read ↗

Candidate genes and neuropsychological phenotypes in children with ADHD: review of association studiesSemantic proximity Read ↗

Association of the dopamine receptor D4 (DRD4) gene 7-repeat allele with children with attention-deficit/hyperactivity disorder (ADHD): an update.Semantic proximity Read ↗

Genetic factors of reaction time performance: DRD4 7-repeat allele associated with slower responses.Semantic proximity Read ↗

Family-based and case-control association studies of DRD4 and DAT1 polymorphisms in Chinese attention deficit hyperactivity disorder patients suggest long repeats contribute to genetic risk for the disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.