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Article

Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorder.

Archives of general psychiatry - 1 Aug 2007

Shaw Philip, Gornick Michele, Lerch Jason, Addington Anjene, Seal Jeffrey, Greenstein Deanna, Sharp Wendy, Evans Alan, Giedd Jay N, Castellanos F Xavier, Rapoport Judith L

Abstract excerpt

CONTEXT: Attention-deficit/hyperactivity disorder (ADHD) is one of the most heritable neuropsychiatric disorders, and a polymorphism within the dopamine D4 receptor (DRD4) gene has been frequently implicated in its pathogenesis. OBJECTIVE: To examine the effects of the 7-repeat microsatellite in the DRD4 gene on clinical outcome and cortical development in ADHD. We drew comparisons with a single nucleotide...

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Source

Identifiers

PMID: 17679637
DOI: 10.1001/archpsyc.64.8.921

Genes

DRD4
DRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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