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Article

Functional genomic analysis reveals overlapping and distinct features of chronologically long-lived yeast populations.

Aging - 1 Mar 2015

Wierman Margaret B, Matecic Mirela, Valsakumar Veena, Li Mingguang, Smith Daniel L, Bekiranov Stefan, Smith Jeffrey S

Abstract excerpt

Yeast chronological lifespan (CLS) is extended by multiple genetic and environmental manipulations, including caloric restriction (CR). Understanding the common changes in molecular pathways induced by such manipulations could potentially reveal conserved longevity mechanisms. We therefore performed gene expression profiling on several long-lived yeast populations, including anade4∆mutant defective in de novo...

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PMID: 25769345
DOI: 10.18632/aging.100729
PMCID: PMC4394729

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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