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Article

Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes.

Open biology - 1 Feb 2015

Kimura Shuhei, Loppin Benjamin

Abstract excerpt

In mammals, the testis-specific bromodomain and extra terminal (BET) protein BRDT is essential for spermatogenesis. In Drosophila, it was recently reported that the tBRD-1 protein is similarly required for male fertility. Interestingly, however, tBRD-1 has two conserved bromodomains in its N-terminus but it lacks an extra terminal (ET) domain characteristic of BET proteins. Here, using proteomics approaches to...

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Identifiers

PMID: 25652540
DOI: 10.1098/rsob.140145
PMCID: PMC4345279

Genes

BRDT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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