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Article

Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability.

The Journal of cell biology - 5 Jan 2015

Pattabiraman Shrivatsav, Baumann Claudia, Guisado Daniela, Eppig John J, Schimenti John C, De La Fuente Rabindranath

Abstract excerpt

Postmeiotic gene expression is essential for development and maturation of sperm and eggs. We report that the dual bromodomain-containing protein BRWD1, which is essential for both male and female fertility, promotes haploid spermatid-specific transcription but has distinct roles in oocyte meioti...

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Identifiers

PMID: 25547156
DOI: 10.1083/jcb.201404109
PMCID: PMC4284233

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25547156-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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