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Article

Mechanical factors direct mouse aortic remodelling during early maturation.

Journal of the Royal Society, Interface - 6 Mar 2015

Le Victoria P, Cheng Jeffrey K, Kim Jungsil, Staiculescu Marius C, Ficker Shawn W, Sheth Saahil C, Bhayani Siddharth A, Mecham Robert P, Yanagisawa Hiromi, Wagenseil Jessica E

Abstract excerpt

Numerous diseases have been linked to genetic mutations that lead to reduced amounts or disorganization of arterial elastic fibres. Previous work has shown that mice with reduced amounts of elastin (Eln+/-) are able to live a normal lifespan through cardiovascular adaptations, including changes in haemodynamic stresses, arterial geometry and arterial wall mechanics. It is not known if the timeline and presence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25652465
DOI: 10.1098/rsif.2014.1350
PMCID: PMC4345501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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