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Article

Discrete contributions of elastic fiber components to arterial development and mechanical compliance.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2009

Carta Luca, Wagenseil Jessica E, Knutsen Russell H, Mariko Boubacar, Faury Gilles, Davis Elaine C, Starcher Barry, Mecham Robert P, Ramirez Francesco

Abstract excerpt

OBJECTIVE: Even though elastin and fibrillin-1 are the major structural components of elastic fibers, mutations in elastin and fibrillin-1 lead to narrowing of large arteries in supravalvular aortic stenosis and dilation of the ascending aorta in Marfan syndrome, respectively. A genetic approach was therefore used here to distinguish the differential contributions of elastin and fibrillin-1 to arterial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19850904
DOI: 10.1161/ATVBAHA.109.193227
PMCID: PMC2797476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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