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Article

Reduced Biaxial Contractility in the Descending Thoracic Aorta of Fibulin-5 Deficient Mice.

Journal of biomechanical engineering - 1 May 2016

Murtada S-I, Ferruzzi J, Yanagisawa H, Humphrey J D

Abstract excerpt

The precise role of smooth muscle cell contractility in elastic arteries remains unclear, but accumulating evidence suggests that smooth muscle dysfunction plays an important role in the development of thoracic aortic aneurysms and dissections (TAADs). Given the increasing availability of mouse models of these conditions, there is a special opportunity to study roles of contractility ex vivo in intact vessels...

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Identifiers

PMID: 26963838
DOI: 10.1115/1.4032938
PMCID: PMC4843850

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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