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Article

Decreased elastic energy storage, not increased material stiffness, characterizes central artery dysfunction in fibulin-5 deficiency independent of sex.

Journal of biomechanical engineering - 1 Mar 2015

Ferruzzi J, Bersi M R, Uman S, Yanagisawa H, Humphrey J D

Abstract excerpt

Central artery stiffness has emerged over the past 15 years as a clinically significant indicator of cardiovascular function and initiator of disease. Loss of elastic fiber integrity is one of the primary contributors to increased arterial stiffening in aging, hypertension, and related conditions...

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Identifiers

PMID: 25532020
DOI: 10.1115/1.4029431
PMCID: PMC4321117

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25532020-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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