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Biomedical Mutation Analysis (BMA): A software tool for analyzing mutations associated with antiviral resistance

2016-08-02

Abstract excerpt

<h4>Introduction: </h4> Hepatitis C virus (HCV) is considered a major public health problem, with 200 million people infected worldwide. The treatment for HCV chronic infection with pegylated interferon alpha plus ribavirin inhibitors is unspecific; consequently, the treatment is effective in only 50% of patients infected. This has prompted the development of direct-acting antivirals (DAA) that target virus protei...

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Literature Corpus work
136589b6-4727-580a-ab0d-7d7df906740f
DOI
10.12688/f1000research.8740.2
Open publication

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