Article
Predicting HIV drug resistance with neural networks.
Bioinformatics (Oxford, England) - 1 Jan 2003
Drăghici Sorin, Potter R Brian
Abstract excerpt
MOTIVATION: Drug resistance is a very important factor influencing the failure of current HIV therapies. The ability to predict the drug resistance of HIV protease mutants may be useful in developing more effective and longer lasting treatment regimens. METHODS: The HIV resistance is predicted to two current protease inhibitors, Indinavir and Saquinavir. The problem was approached from two perspectives. First, a...
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