Article
HIV-1 drug resistance profiling using amino acid sequence space cartography.
Bioinformatics (Oxford, England) - 12 Apr 2022
Pikalyova Karina, Orlov Alexey, Lin Arkadii, Tarasova Olga, Marcou MarcouGilles, Horvath Dragos, Poroikov Vladimir, Varnek Alexandre
Abstract excerpt
MOTIVATION: Human immunodeficiency virus (HIV) drug resistance is a global healthcare issue. The emergence of drug resistance influenced the efficacy of treatment regimens, thus stressing the importance of treatment adaptation. Computational methods predicting the drug resistance profile from genomic data of HIV isolates are advantageous for monitoring drug resistance in patients. However, existing computational...
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