Article
Phenotypic characterization of canine intestinal intraepithelial lymphocytes in dogs with inflammatory bowel disease.
Journal of veterinary internal medicine - 1 Jan 2000
Haas E, Rütgen B C, Gerner W, Richter B, Tichy A, Galler A, Bilek A, Thalhammer J G, Saalmüller A, Luckschander-Zeller N
Abstract excerpt
BACKGROUND: Many dogs suffering from inflammatory bowel disease (IBD) are presented to veterinary clinics. These patients are diagnosed based on a history of chronic gastrointestinal signs and biopsy-confirmed histopathologic intestinal inflammation. Intestinal intraepithelial lymphocytes (IEL) are part of the first line of defense in the gastrointestinal immune system. Alterations in IEL subsets may play a role...
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