Article
Early-onset diffuse gastric cancer associated with a de novo large genomic deletion of CDH1 gene.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association - 1 Oct 2014
Sugimoto Shinya, Yamada Hidetaka, Takahashi Masazumi, Morohoshi Yuichi, Yamaguchi Naotaka, Tsunoda Yuya, Hayashi Hiroyuki, Sugimura Haruhiko, Komatsu Hirokazu
Abstract excerpt
A 41-year-old man with no familial history of gastric cancer was diagnosed as with intramucosal early gastric cancer. Two months after the first endoscopic submucosal dissection for signet-ring cell carcinoma (SRCC), the appearance of previously unrecognized multiple erosions of SRCC was noticed. Pathological examination after a total gastrectomy and Roux-en-Y reconstruction with D2 lymph node dissection were...
Topics
- Adult
- Anastomosis, Roux-en-Y
- Antigens, CD
- Cadherins
- Carcinoma, Signet Ring Cell
- Gastrectomy
- Gene Deletion
- Humans
- Male
- Mutation
- Stomach Neoplasms