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Article

Genotypic and allelic variability in CYP19A1 among populations of African and European ancestry.

PloS one - 1 Jan 2015

Starlard-Davenport Athena, Orloff Mohammed S, Dhakal Ishwori, Penney Rosalind B, Kadlubar Susan A

Abstract excerpt

CYP19A1 facilitates the bioconversion of estrogens from androgens. CYP19A1 intron single nucleotide polymorphisms (SNPs) may alter mRNA splicing, resulting in altered CYP19A1 activity, and potentially influencing disease susceptibility. Genetic studies of CYP19A1 SNPs have been well documented in populations of European ancestry; however, studies in populations of African ancestry are limited. In the present...

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PMID: 25647083
DOI: 10.1371/journal.pone.0117347
PMCID: PMC4315570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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