Article
The heritability of hemolysis in stored human red blood cells.
Transfusion - 1 Jun 2015
Van 't Erve Thomas J, Wagner Brett A, Martin Sean M, Knudson C Michael, Blendowski Robyn, Keaton Mignon, Holt Tracy, Hess John R, Buettner Garry R, Ryckman Kelli K, Darbro Benjamin W, Murray Jeffrey C, Raife Thomas J
Abstract excerpt
BACKGROUND: The transfusion of red blood cells (RBCs) with maximum therapeutic efficacy is a major goal in transfusion medicine. One of the criteria used in determining stored RBC quality is end-of-storage hemolysis. Between donors, a wide range of hemolysis is observed under identical storage conditions. Here, a potential mechanism for this wide range is investigated. We hypothesize that the magnitude of...
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