Article
Distributions of the GSTM1 and GSTT1 null genotypes worldwide are characterized by latitudinal clines.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Saitou Marie, Ishida Takafumi
Abstract excerpt
BACKGROUND: Deletion types of genetic variants of glutathione S-transferase (GST) M1 and T1, the GSTM1 null and GSTT1 null which are risk factors for certain cancers, have been ubiquitously found in human populations but their worldwide distribution pattern is unclear. MATERIALS AND METHODS: To perform a meta-analysis, a systematic search for the literature on GSTM1 and GSTT1 null genotypes was done to identify...
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