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Article

Glutathione S-transferase M1 and T1 null genotypes and the risk of gastric and colorectal cancers.

Cancer letters - 10 Aug 2001

Saadat I, Saadat M

Abstract excerpt

Several polymorphic glutathione S-transferase (GST) enzymes are involved in the detoxification of active metabolites of many potential carcinogens and may therefore be important in modulating susceptibility to cancers. GSTM1 and GSTT1 are polymorphic, and the null alleles result in a lack of corresponding enzyme activities. Previous studies demonstrated that the GSTM1 and GSTT1 null genotypes correlated with an...

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Source

Identifiers

PMID: 11410321
DOI: 10.1016/s0304-3835(01)00550-x

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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