Article
A new look at osteomyelitis development--focus on CCR5delta32. Study in patients from Northeast Brazil.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Apr 2015
de Souza Maria do Socorro Queiroz Alves, de Souza Clinio Alves, Cunha Lia Moreira Pinto, de Souza Argos Queiroz Alves, de Morais Maíra Silva, Rabenhorst Sílvia Helena Barem
Abstract excerpt
INTRODUCTION: CCR5 receptor exerts an important role in the host immune response. Osteomyelitis is an inflammatory process and Staphylococcus aureus is the principal causative agent of this bone injury complication. A deletion of 32bp (CCR5Δ32) in the CCR5 gene seems to protect against HIV-1, S.aureus and other infections. However, the CCR5Δ32 allele has been associated with an increased risk for other diseases....
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