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Article

A link between osteomyelitis and IL1RN and IL1B polymorphisms-a study in patients from Northeast Brazil.

Acta orthopaedica - 1 Oct 2017

Alves De Souza Clinio, Queiroz Alves De Souza Argos, Queiroz Alves De Souza Maria do Socorro, Dias Leite José Alberto, Silva De Morais Maíra, Barem Rabenhorst Sílvia Helena

Abstract excerpt

Background and purpose - Treatment failure of osteomyelitis can result from genetic susceptibility, highlighting polymorphisms of the interleukin-1 (IL-1) family members, central mediators of innate immunity and inflammation. Polymorphisms are DNA sequence variations that are common in the population (1% or more) and represent multiple forms of a single gene. We investigated the association of IL1RNVNTR...

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Identifiers

PMID: 28682145
DOI: 10.1080/17453674.2017.1348439
PMCID: PMC5560221

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