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Article

ANGPTL7 regulates the expansion and repopulation of human hematopoietic stem and progenitor cells

30 Jan 2015

Abstract excerpt

Successful expansion of hematopoietic stem cells would benefit the use of hematopoietic stem cell transplants in the clinic. Several angiopoietin-like proteins, including angiopoietin-like 7, can support the activity of hematopoietic stem cells. However, effects of ANGPTL7 on human hematopoietic stem cells and the downstream signaling cascade activated by ANGPTL7 are poorly understood. Here, we established a...

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PMID: 25637050
DOI: 10.3324/haematol.2014.118612

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