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Article

Human CD34(lo)CD133(lo) fetal liver cells support the expansion of human CD34(hi)CD133(hi) hematopoietic stem cells.

Cellular & molecular immunology - 1 Sept 2016

Yong Kylie Su Mei, Keng Choong Tat, Tan Shu Qi, Loh Eva, Chang Kenneth Te, Tan Thiam Chye, Hong Wanjin, Chen Qingfeng

Abstract excerpt

We have recently discovered a unique CD34(lo)CD133(lo) cell population in the human fetal liver (FL) that gives rise to cells in the hepatic lineage. In this study, we further characterized the biological functions of FL CD34(lo)CD133(lo) cells. Our findings show that these CD34(lo)CD133(lo) cells express markers of both endodermal and mesodermal lineages and have the capability to differentiate into hepatocyte...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27593483
DOI: 10.1038/cmi.2015.40
PMCID: PMC5037276

Genes

CXCL12
IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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