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Article

Pleiotrophin Enhances Clonal Growth and Long-Term Expansion of Human Embryonic Stem Cells

6 Sept 2007

Abstract excerpt

To identify additional growth factors for optimizing propagation of human embryonic stem cells (hESCs), we mined publicly available data sets for the transcriptomes of murine and human ESCs and feeder cells, thereby generating a list of growth factors and complementary receptors. We identified the major pathways previously reported to be important, as well as several new ones. One pathway is the Pleiotrophin...

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PMID: 17823238
DOI: 10.1634/stemcells.2007-0372

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