Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DPP4-deficient congenic rats display blunted stress, improved fear extinction and increased central NPY.

Psychoneuroendocrinology - 1 Mar 2015

Canneva Fabio, Golub Yulia, Distler Joerg, Dobner Julia, Meyer Sandra, von Hörsten Stephan

Abstract excerpt

BACKGROUND: Inhibitors of dipeptidyl peptidase 4 (DPP4, CD26) are used for the treatment of type 2 diabetic patients and better glucose tolerance has been confirmed in functionally DPP4-deficient congenic rats (DPP4mut), along with immunological alterations and, interestingly, a stress-resilient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Congenic
Share to Conditioning, Classical
Share to Dipeptidyl Peptidase 4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Extinction, Psychological

Share to Neuropeptide Y

Share to Receptors, Neuropeptide Y

Share to Stress, Physiological

Source

Identifiers

PMID: 25635612
DOI: 10.1016/j.psyneuen.2015.01.007

Genes

DPP4
NPY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25635612-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DPP4-deficient congenic rats display blunted stress, improved fear extinction and increased central NPY.PMID 25635612Read ↗

Role of hypothalamus-pituitary-adrenal axis modulation in the stress-resilient phenotype of DPP4-deficient rats.Semantic proximity Read ↗

Phenotyping of congenic dipeptidyl peptidase 4 (DP4) deficient Dark Agouti (DA) rats suggests involvement of DP4 in neuro-, endocrine, and immune functions.Semantic proximity Read ↗

Extreme reduction of dipeptidyl peptidase IV activity in F344 rat substrains is associated with various behavioral differences.Semantic proximity Read ↗

The NPB/NPW neuropeptide system and its role in regulating energy homeostasis, pain, and emotion.Semantic proximity Read ↗

Nociceptin Orphanin F/Q Pathways are Dysregulated by Stress and Modulate Reward Learning and Motivation Across SpeciesSemantic proximity Read ↗

Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice.Semantic proximity Read ↗

Altered emotional behaviors in the diabetes mellitus OLETF type 1 congenic rat.Semantic proximity Read ↗

NPY and Y receptors: lessons from transgenic and knockout models.Semantic proximity Read ↗

Behavioural profile of a new mouse model for NPY deficiencySemantic proximity Read ↗

A new model of <i>Pde4d</i> deficiency: genetic knock‐down of PDE4D enzyme in rats produces an antidepressant phenotype without spatial cognitive effectsSemantic proximity Read ↗

UNPREDICTABLE SOUND STRESS MODEL CAUSES MIGRAINE-LIKE BEHAVIORS IN MICE WITH SEXUAL DIMORPHISMSemantic proximity Read ↗

A possible role of neuropeptide Y in depression and stress.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.