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Article

Low prevalence of CHEK2 gene mutations in multiethnic cohorts of breast cancer patients in Malaysia.

PloS one - 1 Jan 2015

Mohamad Suriati, Isa Nurismah Md, Muhammad Rohaizak, Emran Nor Aina, Kitan Nor Mayah, Kang Peter, Kang In Nee, Taib Nur Aishah Mohd, Teo Soo Hwang, Akmal Sharifah Noor

Abstract excerpt

CHEK2 is a protein kinase that is involved in cell-cycle checkpoint control after DNA damage. Germline mutations in CHEK2 gene have been associated with increase in breast cancer risk. The aim of this study is to identify the CHEK2 gene germline mutations among high-risk breast cancer patients an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25629968
DOI: 10.1371/journal.pone.0117104
PMCID: PMC4309602

Genes

CHEK2
BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25629968-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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