Article
Cellular and molecular perspectives in rheumatoid arthritis.
Seminars in immunopathology - 1 Jun 2017
Veale Douglas J, Orr Carl, Fearon Ursula
Abstract excerpt
Synovial immunopathology in rheumatoid arthritis is complex involving both resident and infiltrating cells. The synovial tissue undergoes significant neovascularization, facilitating an influx of lymphocytes and monocytes that transform a typically acellular loose areolar membrane into an invasive tumour-like pannus. The microvasculature proliferates to form straight regularly-branching vessels; however, they are...
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