Article

Identification of genes involved in the effects of hypoxia-inducible factor-2 on articular chondrocytes using bioinformatic analysis and validation in osteoarthritis

2024-01-30

Abstract excerpt

Although over-expression of hypoxia-inducible factor-2 alpha (HIF-2α) can result in cartilage destruction and osteoarthritis (OA) development, the underlying mechanisms remain poorly understood. Here, we investigated the molecular mechanisms in chondrocytes over-expressing HIF-2α. The GeneCloud of Biotechnology Information platform was used to identify differentially expressed genes (DEGs). Using the GEO GSE104794...

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Literature Corpus work: 2b149f35-e771-5c92-b267-ae0a74b3c129
DOI: 10.22541/au.170664313.33367116/v1

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