Article

Identification of genes involved in the effects of hypoxia-inducible factor-2 on articular chondrocytes using bioinformatic analysis and validation in osteoarthritis

2022-05-13

Abstract excerpt

Although over-expression of hypoxia-inducible factor-2 alpha (HIF-2α) can result in cartilage destruction and osteoarthritis (OA) development, the underlying mechanisms remain poorly understood. Here, we investigated the molecular mechanisms in chondrocytes over-expressing HIF-2α. The GeneCloud of Biotechnology Information platform was used to identify differentially expressed genes (DEGs). Using the GEO GSE104794...

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Literature Corpus work: 981f6b4d-5fff-5211-badf-062d5511f21a
DOI: 10.21203/rs.3.rs-1622133/v1

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