Article
Evaluation of Interfering RNA Efficacy in Treating Hepatitis B: Is It Promising?
31 Oct 2024
Abstract excerpt
BACKGROUND: Despite an existing safe and effective vaccine for hepatitis B virus (HBV), it is still a major public health concern. Nowadays, several drugs are used to treat chronic hepatitis B; however, full healing remains controversial. The viral covalently closed circular DNA (cccDNA) formed by HBV forms a major challenge in its treatment, as does the ability of HBV to integrate itself into the host genome,...
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