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Article

Multiple sclerosis risk loci correlate with cervical cord atrophy and may explain the course of disability.

Neurogenetics - 1 Jul 2015

Akkad Denis A, Bellenberg Barbara, Esser Sarika, Weiler Florian, Epplen Jörg T, Gold Ralf, Lukas Carsten, Haghikia Aiden

Abstract excerpt

Genome-wide association studies (GWAS) underscore the genetic basis of multiple sclerosis (MS); however, only few of the newly reported genetic variations relevant in MS have been replicated or correlated for clinical/paraclinical phenotypes such as spinal cord atrophy in independent patient cohorts. We genotyped 141 MS patients for 58 variations reported to reach significance in GWAS. Expanded disability status...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25620546
DOI: 10.1007/s10048-015-0438-0

Genes

BATF
EVI5
NFKB1
PLEK
RGS1
TAGAP
TYK2

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