Article
A multicenter assessment of cervical cord atrophy among MS clinical phenotypes.
Neurology - 14 Jun 2011
Rocca M A, Horsfield M A, Sala S, Copetti M, Valsasina P, Mesaros S, Martinelli V, Caputo D, Stosic-Opincal T, Drulovic J, Comi G, Filippi M
Abstract excerpt
OBJECTIVE: In this multicenter study, a new semiautomatic method for segmenting the cervical cord from C2 to C5 was used to investigate the correlation between cord atrophy and clinical disability in a large sample of patients with multiple sclerosis (MS). METHODS: T2 and 3-dimensional T1-weighted cervical cord scans and dual-echo brain scans were acquired from 143 healthy controls, 22 patients with clinically...
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