Article
Rs37972 and rs37973 single-nucleotide polymorphisms in the glucocorticoid-inducible 1 gene are not associated with asthma risk in a Saudi Arabian population.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Mar 2015
Al-Muhsen Saleh, Vazquez-Tello Alejandro, Jamhawi Amer, Al-Dosari Mohamed S, Mahboub Bassam, Iqbal Nizam, Temsah Mohamed Hani, Al-Eyadhy Ayman, Alharbi Nasser, Halwani Rabih
Abstract excerpt
OBJECTIVE: Rs37972 and rs37973 variants in the glucocorticoid-induced transcript 1 gene have been associated with inhaled glucocorticosteroid responsiveness in asthmatics; however, some discrepancies have been also reported. This study aims to determine whether rs37972 and rs37973 SNPs are associated with asthma risk in Saudi Arabian asthmatics. METHODS: Two-hundred seventy-one diagnosed asthmatics (3-65 years...
Read the complete abstract on PubMed