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Article

Pharmacogenetics of inhaled corticosteroids and exacerbation risk in adults with asthma

15 Jan 2021

Abstract excerpt

BACKGROUND: Inhaled corticosteroids (ICS) are a cornerstone of asthma treatment. However, their efficacy is characterized by wide variability in individual responses. OBJECTIVE: We investigated the association between genetic variants and risk of exacerbations in adults with asthma and how this association is affected by ICS treatment. METHODS: We investigated the pharmacogenetic effect of 10 single nucleotide...

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PMID: 33428814
DOI: 10.1111/cea.13829

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