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Article

Inhibition of phenotypic and functional maturation of dendritic cells by manassantin a.

Journal of pharmacological sciences - 1 Apr 2009

Kim Jee Youn, Kang Jong Soon, Kim Hwan Mook, Kim Young Kook, Lee Hong Kyung, Song Sukgil, Hong Jin Tae, Kim Youngsoo, Han Sang-Bae

Abstract excerpt

Manassantin A (MSA) inhibits nitric oxide production by macrophages through the inhibition of NF-kappaB activation, but the effect of MSA on dendritic cells has not been elucidated yet. Here we investigated the inhibitory effects of MSA on immune functions of dendritic cells (DCs). MSA inhibited lipopolysaccharide (LPS)-induced phenotypic maturation of DCs, which was proved by the decreased expression of CD40,...

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Source

Identifiers

PMID: 19352074
DOI: 10.1254/jphs.08299fp

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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