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Article

Gliadin fragments induce phenotypic and functional maturation of human dendritic cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2005

Palová-Jelínková Lenka, Rozková Daniela, Pecharová Barbara, Bártová Jirina, Sedivá Anna, Tlaskalová-Hogenová Helena, Spísek Radek, Tucková Ludmila

Abstract excerpt

Celiac disease is a chronic inflammatory disease developing in genetically predisposed individuals. Ingested gliadin, the triggering agent of the disease, can cross the epithelial barrier and elicit a harmful T cell-mediated immune response. Dendritic cells (DC) are supposed to play a pivotal role in shaping the immune response. The direction of the immune response toward immunity or tolerance depends on the...

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Identifiers

PMID: 16272365
DOI: 10.4049/jimmunol.175.10.7038

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APC
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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