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Article

Downregulation of CREB Promotes Cell Proliferation by Mediating G<sub>1</sub>/S Phase Transition in Hodgkin Lymphoma

18 Jul 2016

Abstract excerpt

The cyclic-AMP response element-binding protein (CREB), a well-known nuclear transcription factor, has been shown to play an essential role in many cellular processes, including differentiation, cell survival, and cell proliferation, by regulating the expression of downstream genes. Recently, increased expression of CREB was frequently found in various tumors, indicating that CREB is implicated in the process of...

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PMID: 27458098
DOI: 10.3727/096504016x14634208142987

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