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Article

New concepts in breast cancer genomics and genetics.

Breast cancer research : BCR - 1 Jan 2014

Goncalves Rodrigo, Warner Wayne A, Luo Jingqin, Ellis Matthew J

Abstract excerpt

Massively parallel DNA and RNA sequencing approaches have generated data on thousands of breast cancer genomes. In this review, we consider progress largely from the perspective of new concepts and hypotheses raised so far. These include challenges to the multistep model of breast carcinogenesis and the discovery of new defects in DNA repair through sequence analysis. Issues for functional genomics include the...

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PMID: 25606588
DOI: 10.1186/s13058-014-0460-4
PMCID: PMC4384360

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ESR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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