Article
Pharmacogenomics and breast cancer.
Pharmacogenomics - 1 Jan 2004
Lymberis Stella C, Parhar Preeti K, Katsoulakis Evangelia, Formenti Silvia C
Abstract excerpt
Germline variants can be used to study breast cancer susceptibility as well as the variable response to both drug and radiation therapy used in the treatment of breast cancer. In addition to germline high-penetrance mutations important in familial and hereditary breast cancer, a substantial component of breast cancer risk can be attributed to the combined effect of many low-risk germline polymorphisms involved in...
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