Article
Recent advances in molecular genetics of breast cancer.
Journal of molecular medicine (Berlin, Germany) - 1 Oct 2001
Pavelić K, Gall-Troselj K
Abstract excerpt
Breast cancer is among the most common tumors affecting women. It is characterized by a number of genetic aberrations. Some 5-10% of cases are thought to be inherited. The hereditary breast and ovarian cancer syndrome includes genetic alterations of various susceptibility genes, particularly BRCA1 and BRCA2. Breast tumors of patients with germ-line mutations in the BRCA1 and BRCA2 genes have more genetic defects...
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