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Article

Simultaneous Isolation of Enriched Myoblasts and Fibroblasts for Migration Analysis Within a Novel Co-Culture Assay

1 Jan 2015

Abstract excerpt

Skeletal muscle injury elicits the activation of satellite cells and their migration to the wound area for subsequent terminal differentiation and tissue integration. However, interstitial fibroblasts recruited to the site of injury promote deposition of fibrotic tissue, which hampers myoblast-mediated muscle regeneration. Currently, analysis of myoblast migration in vitro can be accomplished using chemotactic,...

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PMID: 25605577
DOI: 10.2144/000114246

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