Emerging concepts on the mechanical interplay between migrating cells and microenvironment in vivo

Abstract excerpt

During embryogenesis, tissues develop into elaborate collectives through a myriad of active mechanisms, with cell migration being one of the most common. As cells migrate, they squeeze through crowded microenvironments to reach the positions where they ultimately execute their function. Much of our knowledge of cell migration has been based on cells’ ability to navigate in vitro and how cells respond to the...

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