Article

Glucocorticoids Mediate Transcriptome-wide Alternative Polyadenylation: Mechanisms and Functional Implications

2022-03-30

Abstract excerpt

<h4>ABSTRACT</h4> Alternative polyadenylation (APA) is a common genetic regulatory mechanism that generates distinct 3′ ends for RNA transcripts. Changes in APA have been associated with multiple biological processes and disease phenotypes. However, the role of hormones and their drug analogs in APA remains largely unknown. In this study, we investigated transcriptome-wide the impact of glucocorticoids on APA in...

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Literature Corpus work: cff02643-5179-59fe-b16a-969a164c911b
DOI: 10.1101/2022.03.30.486468

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