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NAT10 governs uterine function and fertility by stabilizing progesterone receptor mRNA via ac <sup>4</sup> C modification

2025-05-30

Abstract excerpt

The N 4 -acetylcytidine (ac 4 C) modification is one of the most abundant chemical modifications in mammalian transcriptome, which plays a crucial role in regulating gene expression across various biological processes. In this study, we investigate the role of N 4 -acetyltransferase 10 (NAT10), the sole enzyme responsible for catalyzing the ac 4 C modification, in uterine function. Our findings revealed that k...

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Literature Corpus work
63a15c84-61a3-576f-a351-fba2cccfe30c
DOI
10.1101/2025.05.27.656376
Open publication

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NAT10 governs uterine function and fertility by stabilizing progesterone receptor mRNA via ac <sup>4</sup> C modificationDOI 10.1101/2025.05.27.656376
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