Article
Engagement of DYRK2 in proper control for cell division.
Cell cycle (Georgetown, Tex.) - 1 Jan 2015
Nihira Naoe Taira, Yoshida Kiyotsugu
Abstract excerpt
Dysregulation of cell cycle machinery causes abnormal cell division, leading to cancer development. To drive cell cycle properly, expression levels of cell cycle regulators are tightly regulated through the cell cycle. Dual specificity tyrosine phosphorylation-regulated kinase 2 (DYRK2) is a Ser/Thr kinase, and its intracellular functions had not been elucidated for decades. Recent studies have shown that DYRK2...
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