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Article

TERT promoter mutations are associated with distant metastases in papillary thyroid carcinoma.

European journal of endocrinology - 1 Apr 2015

Gandolfi Greta, Ragazzi Moira, Frasoldati Andrea, Piana Simonetta, Ciarrocchi Alessia, Sancisi Valentina

Abstract excerpt

OBJECTIVE: Transcriptional activating mutations in the promoter of the telomerase reverse transcriptase (TERT) gene were reported at high frequency in aggressive poorly differentiated and anaplastic thyroid cancers. By contrast, the relevance of these mutations in the metastatic behavior of well-differentiated thyroid cancer is still to be defined. The aim of this work was to investigate the frequency of TERT...

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Topics

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Share to Carcinoma
Share to Carcinoma, Papillary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Neoplasm Metastasis

Share to Promoter Regions, Genetic

Share to Telomerase

Share to Thyroid Cancer, Papillary

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 25583906
DOI: 10.1530/EJE-14-0837

Genes

TERT
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TERT promoter mutations are associated with distant metastases in papillary thyroid carcinoma.PMID 25583906Read ↗

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