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Article

TERT promoter mutations are a major indicator of recurrence and death due to papillary thyroid carcinomas.

Clinical endocrinology - 1 Aug 2016

Bullock Martyn, Ren Yan, O'Neill Christine, Gill Anthony, Aniss Adam, Sywak Mark, Sidhu Stan, Delbridge Leigh, Learoyd Diana, de Vathaire Florent, Robinson Bruce G, Clifton-Bligh Roderick J

Abstract excerpt

CONTEXT: TERT promoter mutations have been associated with adverse prognosis in papillary thyroid carcinomas (PTCs). OBJECTIVE: We investigated the association between TERT promoter mutations and survival from PTC. DESIGN: Retrospective observational cohort study. PATIENTS: Eighty consecutive patients with PTC who underwent surgery between 1990 and 2003. MEASUREMENTS: TERT promoter was genotyped in DNA from 80...

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Share to Carcinoma, Papillary
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Prognosis

Share to Promoter Regions, Genetic

Share to Recurrence

Share to Survival Rate

Share to Telomerase

Share to Thyroid Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 26667986
DOI: 10.1111/cen.12999
PMCID: PMC5683578

Genes

TERT
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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