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Article

Telomerase reverse transcriptase mutations are independent predictor of disease-free survival in Middle Eastern papillary thyroid cancer.

International journal of cancer - 15 May 2018

Bu Rong, Siraj Abdul K, Divya Sasidharan Padmaja, Kong Yan, Parvathareddy Sandeep Kumar, Al-Rasheed Maha, Al-Obaisi Khadija A S, Victoria Ingrid G, Al-Sobhi Saif S, Al-Dawish Mohammed, Al-Dayel Fouad, Al-Kuraya Khawla S

Abstract excerpt

Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Tumor recurrence occurs in ∼20% of PTCs and some reach advanced stages. Promoter mutation in the telomerase reverse transcriptase (TERT) gene is identified to be a prognostic marker in PTC. However, the contribution of TERT promoter mutation to cancer progression in PTC patients is still not fully understood. In this study, we...

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PMID: 29266240
DOI: 10.1002/ijc.31225

Genes

TERT

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Telomerase reverse transcriptase mutations are independent predictor of disease-free survival in Middle Eastern papillary thyroid cancer.PMID 29266240Read ↗

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